Publications

Publications

For links to abstracts, full text articles and publications by the Legname Laboratory and related resources, please visit PubMed: a service of the National Library of Medicine and the National Institutes of Health.

Legname laboratory publications and related resources

Prion Efficiently Replicates in α-Synuclein Knockout Mice

Journal: 

Molecular Neurobiology

Date: 

30 April, 2019

Mol Neurobiol. 2019 Apr 30. doi: 10.1007/s12035-019-1602-6. [Epub ahead of print]

Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure

Journal: 

Journal of Biological Chemistry

Date: 

12 February, 2019

J Biol Chem. 2019 Feb 12. pii: jbc.RA118.001907. doi: 10.1074/jbc.RA118.001907. [Epub ahead of print]

Copper Binding Regulates Cellular Prion Protein Function

Journal: 

Molecular Neurobiology

Date: 

7 February, 2019

Mol Neurobiol. 2019 Feb 7. doi: 10.1007/s12035-019-1510-9. [Epub ahead of print]

Brain aging: A Ianus-faced player between health and neurodegeneration

Journal: 

Journal of Neuroscience Research

Date: 

11 January, 2019

J Neurosci Res. 2019 Jan 11. doi: 10.1002/jnr.24379.

Synthetic Prion Selection and Adaptation

Journal: 

Molecular Neurobiology

Date: 

3 August, 2018

Mol Neurobiol. 2018 Aug 3. doi: 10.1007/s12035-018-1279-2. [Epub ahead of print]

Conformational properties of intrinsically disordered proteins bound to the surface of silica nanoparticles

Journal: 

Biochimica et Biophysica Acta

Date: 

2 April, 2018

Biochim Biophys Acta. 2018 Apr 2. pii: S0304-4165(18)30088-6. doi: 10.1016/j.bbagen.2018.03.026.

Effects of peptidyl-prolyl isomerase 1 depletion in animal models of prion diseases

Journal: 

Prion

Date: 

4 March, 2018

Prion. 2018 Mar 4;12(2):127-137. doi: 10.1080/19336896.2018.1464367. Epub 2018 May 18.

Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases

Journal: 

Frontiers Neuroscience

Date: 

22 January, 2018

Front Neurosci. 2018 Jan 22;12:8. doi: 10.3389/fnins.2018.00008. eCollection 2018.

The Role Of The Prion Protein In The Internalization Of α-Synuclein Amyloids

Journal: 

Prion

Date: 

8 January, 2018

Prion. 2018 Jan 8:0. doi: 10.1080/19336896.2017.1423186. [Epub ahead of print]

Differential overexpression of SERPINA3 in human prion diseases

Journal: 

Scientific Reports

Date: 

15 November, 2017

Sci Rep. 2017 Nov 15;7(1):15637. doi: 10.1038/s41598-017-15778-8.

Elucidating the function of the prion protein

Journal: 

Plos Pathogens

Date: 

31 August, 2017

PLos Pathog. 2017 Aug 31;13(8):e1006458. doi: 10.1371/journal.ppat.1006458. eCollection 2017 Aug.

Identification of novel fluorescent probes preventing PrPSc replication in prion diseases

Journal: 

European Journal of Medicinal Chemistry

Date: 

1 November, 2016

Eur J Med Chem. 2016 Nov 1. pii: S0223-5234(16)30935-7. doi: 10.1016/j.ejmech.2016.10.064. [Epub ahead of print]

Characterization of prion protein function by focal neurite stimulation

Journal: 

Journal of Cell Science

Date: 

15 October, 2016

J Cell Sci. 2016 Oct 15;129(20):3878-3891. Epub 2016 Sep 2.

 

Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein

Journal: 

Analytical Chemistry

Date: 

6 September, 2016

Anal Chem. 2016 Sep 6;88(17):8468-75. doi: 10.1021/acs.analchem.6b00731. Epub 2016 Aug 12.

Synthetic prions with novel strain-specified properties.

Journal: 

PLOS Pathogen

Date: 

31 December, 2015

PLoS Pathog. 2015 Dec 31;11(12):e1005354. doi: 10.1371/journal.ppat.1005354. eCollection 2015.

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