Project Areas
The team
The Laboratory
Project Areas

Giuseppe Legname

The main focus of his research program is the physiological function of the prion protein in mammals and the mechanisms of prion replication as well as the structural characterization of molecular determinants for prion infectivity.

What are Prion Diseases?

Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of rare, incurable neurodegenerative disorders leading to motor and cognitive impairments, extensive brain damage and neuronal degeneration.


Our laboratory works on the cutting edge to understand Prion diseases from many different angles.