Publications

Publications

For links to abstracts, full text articles and publications by the Legname Laboratory and related resources, please visit PubMed: a service of the National Library of Medicine and the National Institutes of Health.

Legname laboratory publications and related resources

Elucidating the function of the prion protein

Journal: 

Plos Pathogens

Date: 

31 August, 2017

PLos Pathog. 2017 Aug 31;13(8):e1006458. doi: 10.1371/journal.ppat.1006458. eCollection 2017 Aug.

Identification of novel fluorescent probes preventing PrPSc replication in prion diseases

Journal: 

European Journal of Medicinal Chemistry

Date: 

1 November, 2016

Eur J Med Chem. 2016 Nov 1. pii: S0223-5234(16)30935-7. doi: 10.1016/j.ejmech.2016.10.064. [Epub ahead of print]

Characterization of prion protein function by focal neurite stimulation

Journal: 

Journal of Cell Science

Date: 

15 October, 2016

J Cell Sci. 2016 Oct 15;129(20):3878-3891. Epub 2016 Sep 2.

 

Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein

Journal: 

Analytical Chemistry

Date: 

6 September, 2016

Anal Chem. 2016 Sep 6;88(17):8468-75. doi: 10.1021/acs.analchem.6b00731. Epub 2016 Aug 12.

Synthetic prions with novel strain-specified properties.

Journal: 

PLOS Pathogen

Date: 

31 December, 2015

PLoS Pathog. 2015 Dec 31;11(12):e1005354. doi: 10.1371/journal.ppat.1005354. eCollection 2015.

Approaches for discovering anti-prion compounds: lessons learned and challenges ahead

Journal: 

Expert Opinion on Drug Discovery

Date: 

15 February, 2015

Expert Opin Drug Discov. 2015 Apr;10(4):389-97. doi: 10.1517/17460441.2015.1016498. Epub 2015 Feb 15

Prion protein and copper cooperatively protect neurons by modulating NMDA receptor through S-nitrosylation

Journal: 

Antioxidants & Redox Signaling

Date: 

4 February, 2015

Antioxid Redox Signal. 2015 Mar 20;22(9):772-84. doi: 10.1089/ars.2014.6032. Epub 2015 Feb 4.

Structural determinants in prion protein folding and stability

Journal: 

Journal of Molecular Biology

Date: 

11 November, 2014

J Mol Biol. 2014 Nov 11;426(22):3796-810. doi: 10.1016/j.jmb.2014.09.017. Epub 2014 Oct 2.

Synthetic prions and other human neurodegenerative proteinopathies

Journal: 

Virus Research

Date: 

31 October, 2014

Virus Res. 2014 Oct 31. pii: S0168-1702(14)00437-7. doi: 10.1016/j.virusres.2014.10.020.

Prion protein and aging

Journal: 

Frontiers in Cell and Developmental Biology

Date: 

29 August, 2014

Front Cell Dev Biol. 2014 Aug 29;2:44. doi: 10.3389/fcell.2014.00044. eCollection 2014. Review.

Prion protein interaction with soil humic substances: environmental implications

Journal: 

PLoS ONE

Date: 

17 June, 2014

PLoS One. 2014 Jun 17;9(6):e100016. doi: 10.1371/journal.pone.0100016. eCollection 2014.

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